RCUK’s expert anaphylaxis group is currently updating the anaphylaxis guidelines for 2021. In light of the current mass vaccination programme we have provided updated information for use in any vaccination setting to give clear guidance to healthcare professionals involved. We have also produced a poster of the algorithm for the management of anaphylaxis in the vaccination setting.
On 4th January 2021, we also published an additional guidance document that clarifies our guidance on the provision of oxygen within the vaccination setting.
Anaphylaxis following vaccination is rare, occurring at less than 1 per million doses for vaccines in the UK. COVID-19 vaccines are new, so it is uncertain if the risk of anaphylaxis is higher compared to other vaccines.
We are encouraging centres providing the COVID-19 vaccination to follow this guidance which we have written in collaboration with the British Society for Allergy and Clinical Immunology, Public Health England and the Royal College of General Practitioners. Our more general anaphylaxis guidance remains current for other settings and can be found here.